[Clinical observation of phenytoin in promoting fracture healing]

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 1999 Nov;13(6):343-5.
[Article in Chinese]

Abstract

Objective: To observe the promoting effect of phenytoin on fracture healing.

Methods: Fourty cases with close fractures of tibia and fibula were included and divided into two groups randomly: the experimental group was administrated with phenytoin and Chinese traditional drug-Jiegudan orally, while the control group was given Jiegudan only. Longitudinal percussion pain, clinical healing time of fracture, growth of calus in X-ray film were detected to evaluate the clinical result.

Results: All the fractures were healed in 3 months. But the experimental group was superior to the control group in all indexes.

Conclusion: Administration of phenytoin orally can markedly promote fracture healing.

Publication types

  • Clinical Trial
  • English Abstract
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Female
  • Fibula / injuries*
  • Fracture Healing / drug effects*
  • Fractures, Closed / drug therapy*
  • Humans
  • Male
  • Middle Aged
  • Phenytoin / therapeutic use*
  • Tibial Fractures / drug therapy*

Substances

  • Phenytoin