Nonmyeloablative bone marrow transplantation based on deletion of host-anti-donor alloreactive cells prevents autoimmune insulitis and diabetes in nonobese diabetic mice

Transplant Proc. 2002 Jun;34(4):1303-6. doi: 10.1016/s0041-1345(02)02745-8.

Authors

G Elkin¹, T B Prighozina, O Gurevitch, S Slavin

Affiliation

¹ Department of Bone Marrow Transplantation,The Cancer Immunotherapy & Cancer Immunobiology Research Center, Hadassah University Hospital, Jerusalem, Israel.

PMID: 12072346
DOI: 10.1016/s0041-1345(02)02745-8

No abstract available

MeSH terms

Animals
Autoimmune Diseases / immunology*
Blood Glucose / metabolism
Bone Marrow Transplantation / immunology*
Bone Marrow Transplantation / methods
Diabetes Mellitus, Type 1 / epidemiology
Diabetes Mellitus, Type 1 / immunology
Diabetes Mellitus, Type 1 / surgery*
Isoantibodies / immunology*
Lymphocyte Depletion*
Mice
Mice, Inbred C57BL
Mice, Inbred NOD
Pancreatic Diseases / immunology*
Transplantation Chimera
Transplantation, Homologous / immunology

Substances

Blood Glucose
Isoantibodies