Malignant mullerian mixed tumor arising from ovarian serous carcinoma: a clinicopathologic and molecular study of two cases

Alberto Gallardo; Xavier Matias-Guiu; Helena Lagarda; Lluis Catasus; Elena Bussaglia; Esther Gras; Daniel Suarez; Jaime Prat

doi:10.1097/00004347-200207000-00010

Malignant mullerian mixed tumor arising from ovarian serous carcinoma: a clinicopathologic and molecular study of two cases

Int J Gynecol Pathol. 2002 Jul;21(3):268-72. doi: 10.1097/00004347-200207000-00010.

Authors

Alberto Gallardo¹, Xavier Matias-Guiu, Helena Lagarda, Lluis Catasus, Elena Bussaglia, Esther Gras, Daniel Suarez, Jaime Prat

Affiliation

¹ Department of Pathology, Hospital Santa Creu i Sant Pau, Autonomous University of Barcelona, Spain.

PMID: 12068173
DOI: 10.1097/00004347-200207000-00010

Abstract

The clinical, histologic, and molecular pathologic features of two cases of malignant mullerian mixed tumor (MMMT) arising from ovarian papillary serous carcinoma are presented. Identical p53 mutations were detected in the primary ovarian carcinoma and the subsequent MMMT in each case.

MeSH terms

Aged
Cystadenocarcinoma, Serous / genetics
Cystadenocarcinoma, Serous / pathology*
Douglas' Pouch / pathology
Female
Genes, p53 / genetics
Humans
Loss of Heterozygosity
Mixed Tumor, Mullerian / genetics
Mixed Tumor, Mullerian / pathology*
Neoplasm Recurrence, Local / genetics
Neoplasm Recurrence, Local / pathology*
Ovarian Neoplasms / genetics
Ovarian Neoplasms / pathology*
Point Mutation