A Toc75-like protein import channel is abundant in chloroplasts

EMBO Rep. 2002 Jun;3(6):557-62. doi: 10.1093/embo-reports/kvf110. Epub 2002 May 24.

Abstract

Chloroplasts import post-translationally most of their constituent polypeptides via two distinct translocon units located in the outer and inner envelope. The protein import channel of the translocon of the outer envelope of chloroplasts, Toc75, is the most abundant protein in that membrane. We identify a novel Toc75 homologous protein, atToc75-V, a prominent protein that is clearly localized in the chloroplastic outer envelope. Phylogenetic analysis indicates that Toc75-V is more closely related to its prokaryotic ancestors than to Toc75 from plants. The presence of a second translocation channel suggests that alternative, previously unrecognized import routes into chloroplasts might exist.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Chloroplasts / chemistry*
  • Membrane Proteins / analysis
  • Membrane Proteins / chemistry*
  • Membrane Proteins / genetics
  • Molecular Sequence Data
  • Pisum sativum / chemistry*
  • Plant Proteins*
  • Protein Precursors / analysis
  • Protein Precursors / chemistry*
  • Protein Precursors / genetics
  • Sequence Homology, Amino Acid

Substances

  • Membrane Proteins
  • OEP75 protein precursor, plant
  • Plant Proteins
  • Protein Precursors