[Deposition of keinoid fibers in gastrointestinal stromal tumors of the small intestine. Report of two cases and review of the literature]

Pathologe. 2002 Mar;23(2):140-4. doi: 10.1007/s00292-001-0499-8.
[Article in German]

Abstract

Skeinoid fibers are interstitial collections of a pathological collagen, most often seen in gastrointestinal stromal tumors. They were first described in 1991. We report two cases of intestinal stromal tumors, one in an exceptionally young patient with excessive skeinoid fiber deposition. The microscopic as well as the ultrastructural findings of skeinoid fibers are demonstrated and their role is discussed considering the newest literature.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adult
  • Antigens, CD34 / analysis
  • Collagen / analysis*
  • Humans
  • Immunohistochemistry
  • Intestinal Neoplasms / pathology*
  • Intestinal Neoplasms / ultrastructure
  • Male
  • Microscopy, Electron
  • Middle Aged
  • Stromal Cells / pathology*
  • Stromal Cells / ultrastructure

Substances

  • Antigens, CD34
  • Collagen