[Long-term follow-up and bone imaging in acquired osteochondrodysplasia in a female patient with thalassemia and desferrioxamine hypersensitivity]

Minerva Pediatr. 2000 Apr;52(4):235-41.
[Article in Italian]

Abstract

We report a female thalassaemia major patient who developed short stature and osteochondrodystrophic lesions during therapy with desferrioxamine (DFX). Healing was noted after the dose of DFX was decreased for 3 years. Unfortunately the spinal cartilage abnormalities did not change suggesting an irreversibility of the ossification process.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Deferoxamine / adverse effects*
  • Drug Hypersensitivity / etiology*
  • Female
  • Follow-Up Studies
  • Humans
  • Infant
  • Iron Chelating Agents / adverse effects*
  • Osteochondrodysplasias / chemically induced*
  • Time Factors
  • beta-Thalassemia / drug therapy*

Substances

  • Iron Chelating Agents
  • Deferoxamine