Spoilt for choice: protein target selection in a time of plenty

Acta Crystallogr D Biol Crystallogr. 2002 May;58(Pt 5):875-7. doi: 10.1107/s0907444902004031. Epub 2002 Apr 26.

Abstract

Experiences in the application of Boolean logic to the clusters of orthologous groups of proteins (COGs) database for target selection in the Mycobacterium tuberculosis genome are described.

MeSH terms

  • Bacterial Proteins / chemistry*
  • Bacterial Proteins / genetics*
  • Databases, Protein
  • Gene Deletion
  • Genes, Bacterial / genetics*
  • Genes, Essential / genetics
  • Genome, Bacterial*
  • Genomics / methods*
  • Mycobacterium leprae / genetics*
  • Mycobacterium tuberculosis / genetics*
  • Phenotype
  • Phylogeny
  • Proteomics / methods*

Substances

  • Bacterial Proteins