[Anaphylaxis after rocuronium: advantage of blood tests for early diagnosis]

Ann Fr Anesth Reanim. 2002 Mar;21(3):221-3. doi: 10.1016/s0750-7658(02)00573-7.
[Article in French]

Abstract

A 56-year-old patient was scheduled for coronary artery bypass surgery, because of a severe coronary artery disease. Soon after induction of anaesthesia, he rapidly developed a cardiovascular collapse with bronchospasm and rash. Specific immunoglobulin E and tryptase measurements supported the diagnosis of grade III anaphylactic shock due to rocuronium bromide. A few days later, a general anaesthesia was administered without muscle relaxant and was uneventful.

Publication types

  • Case Reports

MeSH terms

  • Anaphylaxis / diagnosis*
  • Anaphylaxis / etiology*
  • Androstanols / adverse effects*
  • Coronary Artery Bypass
  • Hematologic Tests
  • Humans
  • Immunoglobulin E / analysis
  • Intraoperative Complications / diagnosis*
  • Intraoperative Complications / etiology*
  • Middle Aged
  • Neuromuscular Nondepolarizing Agents / adverse effects*
  • Preanesthetic Medication
  • Rocuronium
  • Serine Endopeptidases / blood
  • Tryptases

Substances

  • Androstanols
  • Neuromuscular Nondepolarizing Agents
  • Immunoglobulin E
  • Serine Endopeptidases
  • Tryptases
  • Rocuronium