Threefold symmetric trimetallic macrocycles formed via the Weak-Link Approach

Proc Natl Acad Sci U S A. 2002 Apr 16;99(8):4927-31. doi: 10.1073/pnas.072690599. Epub 2002 Apr 9.

Abstract

The synthesis and characterization of a new threefold symmetric hemilabile phosphino-alkylthioether ligand are described. This ligand can be used in combination with Rh(I) and Ir(I) precursor complexes to prepare 40-membered macrocyles with threefold symmetry via the Weak-Link Approach. Synthesis and characterization of two such structures are reported along with a single crystal x-ray diffraction analysis of one of the key intermediates in the case of Rh(I). This is a demonstration of the viability of the Weak-Link Approach for preparing structures other than bimetallic macrocycles and suggests that it could be generalized for a wide range of higher symmetry structures through appropriate hemilabile ligand design.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Crystallography, X-Ray / methods
  • Ligands
  • Macromolecular Substances
  • Magnetic Resonance Spectroscopy
  • Models, Chemical*
  • Models, Molecular
  • Protein Conformation
  • Temperature

Substances

  • Ligands
  • Macromolecular Substances