Chloramphenicol in the 21st century

Hosp Med. 2002 Mar;63(3):157-61. doi: 10.12968/hosp.2002.63.3.2061.

Abstract

Chloramphenicol use has declined in the UK, despite it remaining highly active against a wide range of bacteria. This article will review the activity, pharmacology, toxicology, uses and potential uses of chloramphenicol in an era of increasing antimicrobial resistance.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / adverse effects
  • Anti-Bacterial Agents / pharmacology*
  • Anti-Bacterial Agents / therapeutic use
  • Bacterial Infections / drug therapy*
  • Chloramphenicol / adverse effects
  • Chloramphenicol / pharmacology*
  • Chloramphenicol / therapeutic use
  • Chloramphenicol Resistance
  • Humans
  • Protein Synthesis Inhibitors / adverse effects
  • Protein Synthesis Inhibitors / pharmacology
  • Protein Synthesis Inhibitors / therapeutic use

Substances

  • Anti-Bacterial Agents
  • Protein Synthesis Inhibitors
  • Chloramphenicol