Total syntheses of (-)-fumiquinazolines C, E, and H

Org Lett. 2002 Apr 4;4(7):1087-90. doi: 10.1021/ol017215d.

Abstract

[structure: see text] Total syntheses of the heptacyclic fumiquinazolines C and H have been accomplished efficiently using FmocNHCH(CH2SePh)CO2H as the precursor for the requisite dehydrofumiquinazoline.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Antibiotics, Antineoplastic / chemical synthesis*
  • Aspergillus fumigatus / chemistry
  • Crystallography, X-Ray
  • Cyclization
  • Indicators and Reagents
  • Quinazolines / chemical synthesis*
  • Stereoisomerism

Substances

  • Antibiotics, Antineoplastic
  • Indicators and Reagents
  • Quinazolines
  • fumiquinazoline C
  • fumiquinazoline E
  • fumiquinazoline H