Abstract
La Crosse virus is maintained in a cycle involving mosquitoes and small mammals. Vertebrate cell infection is generally cytolytic; vector cell infection results in persistent infection. Features of La Crosse virus replication that may permit the virus to traffic between vector and vertebrate hosts and condition different infection outcomes are described.
Publication types
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Research Support, U.S. Gov't, P.H.S.
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Review
MeSH terms
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Aedes / growth & development
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Aedes / virology
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Amino Acid Sequence
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Animals
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Culicidae / virology*
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Disease Transmission, Infectious
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Encephalitis, California / transmission
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Host-Parasite Interactions
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Humans
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Infectious Disease Transmission, Vertical
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La Crosse virus / genetics*
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La Crosse virus / growth & development*
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Mammals / virology*
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Mice
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Models, Genetic
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Virus Replication