Effect of dry and humidified gases on the respiratory epithelium in rabbits

J Pediatr Surg. 1975 Oct;10(5):583-92. doi: 10.1016/0022-3468(75)90360-7.

Abstract

A laboratory study was conducted in rabbits to compare histologic changes in the lungs and bronchi after prolonged dry anesthesia and humidified anesthesia. Dry anesthesia caused severe damage to the respiratory epithelium, which was not observed with humidified controls.

MeSH terms

  • Anesthesia, Inhalation / adverse effects*
  • Animals
  • Body Temperature
  • Bronchi / pathology*
  • Bronchial Diseases / etiology
  • Bronchial Diseases / pathology
  • Epithelium / pathology
  • Gases*
  • Humidity*
  • Intubation, Intratracheal
  • Lung / pathology*
  • Nitrous Oxide
  • Oxygen
  • Rabbits
  • Respiratory Tract Diseases / etiology
  • Temperature
  • Time Factors

Substances

  • Gases
  • Nitrous Oxide
  • Oxygen