A new case of acute nonlymphocytic leukemia (French-American-British subtype M1) with double minutes and c-MYC amplification

Natàlia Rodon; Francesc Solé; Blanca Espinet; Marta Salido; Lourdes Zamora; Juan Cruz Cigudosa; Soledad Woessner; Lourdes Florensa

doi:10.1016/s0165-4608(01)00557-x

A new case of acute nonlymphocytic leukemia (French-American-British subtype M1) with double minutes and c-MYC amplification

Cancer Genet Cytogenet. 2002 Jan 15;132(2):161-4. doi: 10.1016/s0165-4608(01)00557-x.

Authors

Natàlia Rodon¹, Francesc Solé, Blanca Espinet, Marta Salido, Lourdes Zamora, Juan Cruz Cigudosa, Soledad Woessner, Lourdes Florensa

Affiliation

¹ Laboratori de Citogenètica i Biologia Molecular, Departament de Patologia, Hospital del Mar, IMAS, Barcelona, Spain.

PMID: 11850082
DOI: 10.1016/s0165-4608(01)00557-x

Abstract

Herein, we present a new case of acute nonlymphocytic leukemia (ANLL) French-American-British M1 subtype with presence of multiple double minutes (dmin) derived from the amplification of the c-MYC oncogene. A review of dmins in ANLL is presented.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Aged
Aged, 80 and over
Chromosome Banding
Female
Gene Amplification*
Genes, myc*
Humans
In Situ Hybridization, Fluorescence
Leukemia, Myeloid, Acute / genetics*