Echinodolides A and B, new cembrane diterpenoids with an eight-membered lactone ring from the leaves of Echinodorus macrophyllus

J Nat Prod. 2002 Jan;65(1):82-4. doi: 10.1021/np0104119.

Abstract

Two new cembrane diterpenoids with an eight-membered lactone ring, echinodolides A (1) and B (2), were isolated from the leaves of the Brazilian medicinal plant Echinodorus macrophyllus ("Chapéu-de-couro"), and the structures and relative stereochemistry were elucidated from their spectroscopic data.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Brazil
  • Chromatography, High Pressure Liquid
  • Circular Dichroism
  • Diterpenes / chemistry
  • Diterpenes / isolation & purification*
  • Lactones / chemistry
  • Lactones / isolation & purification*
  • Magnoliopsida / chemistry*
  • Molecular Conformation
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Plant Leaves / chemistry
  • Plants, Medicinal / chemistry*
  • Spectrometry, Mass, Electrospray Ionization
  • Spectrophotometry, Infrared
  • Stereoisomerism

Substances

  • Diterpenes
  • Lactones
  • echinodolide A
  • echinodolide B