Squamous cell carcinoma arising in the skin of a deltopectoral flap 27 years after pharyngeal reconstruction

Abstract

Background: Development of a second primary squamous cell carcinoma in the skin of a flap used for pharyngeal reconstruction is rare.

Methods: A case of squamous cell carcinoma is presented arising in a deltopectoral flap used to reconstruct the hypopharynx 27 years after total laryngectomy. Three previous reports found on review of the literature are summarized.

Results: A second primary squamous cell carcinoma may arise in the skin of a myocutaneous flap in the absence of any obvious risk factors.

Conclusion: We suspect that long-term exposure of the skin of the flap lining the pharynx to saliva may have been a significant factor in the development of this malignancy. Long-term follow up and awareness of this complication is required for patients with soft tissue reconstruction of the oral cavity and pharynx.