Why measure thiopurine methyltransferase activity? Direct administration of 6-thioguanine might be the alternative for 6-mercaptopurine or azathioprine

Gut. 2001 Dec;49(6):874. doi: 10.1136/gut.49.6.874a.
No abstract available

Publication types

  • Letter
  • Comment

MeSH terms

  • Antimetabolites, Antineoplastic / adverse effects
  • Antimetabolites, Antineoplastic / therapeutic use*
  • Azathioprine / adverse effects
  • Azathioprine / therapeutic use
  • Biomarkers / blood
  • Humans
  • Inflammatory Bowel Diseases / drug therapy*
  • Mercaptopurine / therapeutic use
  • Methyltransferases / blood
  • Pilot Projects
  • Prospective Studies
  • Thioguanine / adverse effects
  • Thioguanine / therapeutic use*

Substances

  • Antimetabolites, Antineoplastic
  • Biomarkers
  • Mercaptopurine
  • Methyltransferases
  • thiopurine methyltransferase
  • Thioguanine
  • Azathioprine