Arp2/3 complex: advances on the inner workings of a molecular machine

Cell. 2001 Dec 14;107(6):703-5. doi: 10.1016/s0092-8674(01)00605-5.

Abstract

Several new papers report progress on the structure and function of Arp2/3 complex. A crystal structure, a cryo-EM structure, and a reconstitution of the complex from subunits have been reported. New results also address the nucleation mechanism and the role of bound nucleotide.

Publication types

  • Review

MeSH terms

  • Actin-Related Protein 2
  • Actin-Related Protein 3
  • Actins / chemistry*
  • Actins / metabolism*
  • Animals
  • Cytoskeletal Proteins*
  • Models, Molecular
  • Protein Structure, Quaternary
  • Protein Subunits

Substances

  • Actin-Related Protein 2
  • Actin-Related Protein 3
  • Actins
  • Cytoskeletal Proteins
  • Protein Subunits