Pulmonary adenocarcinoma simulating malignant mesothelioma

Arch Pathol Lab Med. 2001 Dec;125(12):1598-600. doi: 10.5858/2001-125-1598-PASMM.

Abstract

Adenocarcinoma of the lung with pleural involvement frequently resembles pleural epithelioid mesothelioma clinically as well as macro- and microscopically. Special stains, immunohistochemical studies, and electron microscopic studies are needed to differentiate these 2 tumors. We report a case of pleural involvement by adenocarcinoma, mimicking in the hematoxylin-eosin stain an epithelioid mesothelioma, correctly identified only after immunohistochemical and electron microscopic examinations.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma / chemistry
  • Adenocarcinoma / pathology*
  • Biomarkers, Tumor / analysis
  • Diagnosis, Differential
  • Epithelioid Cells / pathology
  • Female
  • Humans
  • Immunohistochemistry
  • Lung Neoplasms / chemistry
  • Lung Neoplasms / pathology*
  • Male
  • Mesothelioma / chemistry
  • Mesothelioma / pathology*
  • Microscopy, Electron
  • Microvilli / ultrastructure
  • Pleura / chemistry
  • Pleura / pathology
  • Pleura / surgery
  • Pleural Effusion, Malignant / chemistry
  • Pleural Effusion, Malignant / pathology
  • Pleural Neoplasms / chemistry
  • Pleural Neoplasms / secondary

Substances

  • Biomarkers, Tumor