Cell engulfment, no sooner ced than done

Dev Cell. 2001 Oct;1(4):445-7. doi: 10.1016/s1534-5807(01)00065-x.

Abstract

Three genes, ced-2, ced-5, and ced-10, are required for both cell corpse engulfment and distal tip cell migration in C. elegans. Recently, a fourth gene, ced-12, has been identified that is required for these two processes. ced-12 encodes a novel, conserved adaptor molecule involved in the activation of Rho/Rac/CDC42-like GTPases.

Publication types

  • Comment

MeSH terms

  • Animals
  • Apoptosis Regulatory Proteins
  • Caenorhabditis elegans
  • Caenorhabditis elegans Proteins*
  • Carrier Proteins / physiology
  • Cytoskeletal Proteins*
  • Helminth Proteins / physiology*
  • Membrane Proteins / physiology*
  • Phagocytosis / physiology*
  • Protein Kinases / physiology*
  • Proto-Oncogene Proteins c-crk
  • Proto-Oncogene Proteins*
  • rac GTP-Binding Proteins*

Substances

  • Apoptosis Regulatory Proteins
  • CED-10 protein, C elegans
  • CED-12 protein, C elegans
  • CED-5 protein, C elegans
  • Caenorhabditis elegans Proteins
  • Carrier Proteins
  • Cytoskeletal Proteins
  • Helminth Proteins
  • Membrane Proteins
  • Proto-Oncogene Proteins
  • Proto-Oncogene Proteins c-crk
  • Protein Kinases
  • rac GTP-Binding Proteins