Wounds are unique in so far as no disease process other than wounds would have existed from the beginning of mankind. Over the years, the management of wounds, especially that of chronic wounds, has had enormous social and economic implications worldwide. With an aging population, this impact is likely to increase. In recent years, this has been reflected by the birth and rapid growth of the new speciality of 'wound healing'. Continuous advances made in the study of the wound microenvironment, an ever-broadening understanding of the pathophysiology of wounds, and improved techniques in monitoring the response of healing have led to continuing developments in the treatment of chronic wounds. Current research focuses on growth factors and human skin substitutes that provide promising results. This article reviews advances made in wound care management over the years. Despite all these advances, it must be borne in mind that basic principles of wound care in a multidisciplinary team setting still remain the backbone of wound management.