Chondrosarcoma is the most frequent mesenchymal tumor (nonepithelial) of the larynx. Radiographic studies and collaboration of pathologists have allowed that the number of cases diagnosed has increased considerably in the last few years. His privileged site is the subglotics. The late apparition of the symptoms delay the diagnosis, which is guided by CT scan and will be confirmed by histological examination of the surgical piece. The histological distinction between the different degrees of malignancy constitutes one challenge for the pathologist, so far, various criteria have been described for that aim. This biological behaviour is characterized by locoregional recurrence, in direct correlation with the grade of dedifferentiation. The treatment of choice is conservative surgical resection, and a regular follow up is obliged for early detection of recurrences and metastases. A case treated in our Center is presented, and the conclusions obtained after a literature review of the subject.