Contraception and pregnancy after liver transplantation

Liver Transpl. 2001 Nov;7(11 Suppl 1):S74-6. doi: 10.1053/jlts.2001.28644.

Abstract

1. Libido returns promptly after liver transplantation; patients should be counseled on contraception and avoidance of sexually transmitted diseases. 2. Women after liver transplantation are at increased risk for cancer and should have regularly scheduled screening for cervical and breast cancer. 3. Immunosuppression during pregnancy is not teratogenic and does not lead to congenital anomalies. 4. Pregnancy after liver transplantation is often successful, but must be regarded as high risk, associated with an increased risk for hypertension and preeclampsia, intrauterine growth retardation, and prematurity. It is best delayed until 1 to 2 years after grafting. 5. Close monitoring of immunosuppressant levels in the blood is crucial during pregnancy to avoid inappropriately low levels of immunosuppression.

Publication types

  • Review

MeSH terms

  • Contraception*
  • Female
  • Humans
  • Immunosuppressive Agents / adverse effects
  • Immunosuppressive Agents / therapeutic use
  • Liver Transplantation* / adverse effects
  • Postoperative Period
  • Pregnancy / physiology*
  • Pregnancy Complications / chemically induced

Substances

  • Immunosuppressive Agents