[Pemphigoid gestationis and bullous lesions in the newborn]

Arch Pediatr. 2001 Oct;8(10):1071-4. doi: 10.1016/s0929-693x(01)00585-1.
[Article in French]

Abstract

Background: Pemphigoid gestations is very seldom responsible for cutaneous lesions in newborns through passive transfer of the autoimmune disease from mother to infant.

Case report: We report an additional case of a newborn presenting with an extensive but transitory bullous eruption despite the absence of circulating autoantibodies.

Conclusion: Such examples of transplacental pemphigoid are so uncommon that the pathogenic role of IgG autoantibodies is being questioned.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adult
  • Autoantibodies / analysis
  • Autoantibodies / immunology
  • Female
  • Humans
  • Immunoglobulin G / immunology
  • Infant, Newborn
  • Infant, Newborn, Diseases
  • Male
  • Maternal-Fetal Exchange*
  • Pemphigoid, Bullous / immunology*
  • Pemphigoid, Bullous / pathology
  • Pregnancy

Substances

  • Autoantibodies
  • Immunoglobulin G