Increased prevalence of class I integrons in Escherichia coli, Klebsiella species, and Enterobacter species isolates over a 7-year period in a German university hospital

J Clin Microbiol. 2001 Oct;39(10):3724-6. doi: 10.1128/JCM.39.10.3724-3726.2001.

Abstract

The prevalence of integrons in five enterobacterial species was analyzed in 900 blood culture isolates from 1993, 1996, and 1999. Remarkably, the prevalence increased from 4.7% in 1993 to 9.7% in 1996 and finally to 17.4% in 1999 (P < 0.01). Within 7 years the combined percentage of P1 strong promoters and P1 weak plus P2 active promoters with high transcription efficacies has increased from 23.1 to 33.3 and finally 60% (P < 0.05).

MeSH terms

  • Blood / microbiology
  • Culture Media
  • DNA Transposable Elements*
  • Enterobacter / genetics
  • Enterobacter / isolation & purification
  • Enterobacteriaceae / genetics*
  • Enterobacteriaceae / isolation & purification
  • Enterobacteriaceae Infections / epidemiology*
  • Enterobacteriaceae Infections / microbiology*
  • Escherichia coli / genetics
  • Escherichia coli / isolation & purification
  • Germany / epidemiology
  • Hospitals, University*
  • Humans
  • Integrases / genetics*
  • Klebsiella / genetics
  • Klebsiella / isolation & purification
  • Prevalence

Substances

  • Culture Media
  • DNA Transposable Elements
  • Integrases