Temperature induces variations in the retinal cell proliferation rate in a cyprinid

Brain Res. 2001 Sep 21;913(2):190-4. doi: 10.1016/s0006-8993(01)02804-9.

Abstract

We quantitatively evaluate the changes of the proliferative cell populations in the adult tench retinas maintained at 6 degrees C and 20 degrees C by both PCNA antigen detection and flow cytometry-based DNA measurements. Both the overall percentage of S-phase cells in the whole retinas and the number of PCNA-positive cells in each of the retinal layers were significantly lower in the tench kept at 6 degrees C, indicating that temperature affects the retinal germinal cell proliferation.

MeSH terms

  • Animals
  • Body Temperature / physiology*
  • Cell Differentiation / physiology
  • Cell Division / physiology*
  • Cell Lineage / physiology
  • Cell Size / physiology
  • Cyprinidae / anatomy & histology
  • Cyprinidae / growth & development*
  • Cyprinidae / metabolism
  • DNA / metabolism
  • Flow Cytometry
  • Immunohistochemistry
  • Models, Animal
  • Nerve Regeneration / physiology
  • Neuroglia / cytology
  • Neuroglia / metabolism
  • Neurons / cytology
  • Neurons / metabolism*
  • Photoreceptor Cells / cytology
  • Photoreceptor Cells / metabolism
  • Proliferating Cell Nuclear Antigen / metabolism
  • Retina / cytology
  • Retina / growth & development*
  • Retina / metabolism
  • Retinal Ganglion Cells / cytology
  • Retinal Ganglion Cells / metabolism
  • Stem Cells / metabolism*

Substances

  • Proliferating Cell Nuclear Antigen
  • DNA