Resumption of driving after life-threatening ventricular tachyarrhythmia

N Engl J Med. 2001 Aug 9;345(6):391-7. doi: 10.1056/NEJM200108093450601.

Abstract

Background: Although the privilege of driving must be respected, it may be necessary to restrict driving when it poses a threat to others. The risks associated with allowing patients with life-threatening ventricular tachyarrhythmias to drive have not been quantified.

Methods: The Antiarrhythmics versus Implantable Defibrillators (AVID) trial compared antiarrhythmic-drug therapy with the implantation of defibrillators in patients resuscitated from near-fatal ventricular arrhythmias. In the current study, we sent patients who participated in the AVID trial a questionnaire, to be completed anonymously, requesting information about driving habits and experiences.

Results: The questionnaire was returned by 758 of 909 patients (83 percent). Of these, 627 patients drove during the year before their index episode of ventricular tachyarrhythmia. A total of 57 percent of these patients resumed driving within 3 months after randomization in the AVID trial, 78 percent within 6 months, and 88 percent within 12 months. While driving, 2 percent had a syncopal episode, 11 percent had dizziness or palpitations that necessitated stopping the vehicle, 22 percent had dizziness or palpitations that did not necessitate stopping the vehicle, and 8 percent of the 295 patients with an implantable cardioverter-defibrillator received a shock. Fifty patients reported having at least 1 accident, for a total of 55 accidents during 1619 patient-years of follow-up after the resumption of driving (3.4 percent per patient-year). Only 11 percent of these accidents were preceded by symptoms of possible arrhythmia (0.4 percent per patient-year).

Conclusions: Most patients with ventricular tachyarrhythmias resume driving early. Although it is common for them to have symptoms of possible arrhythmia while driving, accidents are uncommon and occur with a frequency that is lower than the annual accident rate of 7.1 percent in the general driving population of the United States.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Accidents, Traffic / statistics & numerical data*
  • Aged
  • Anti-Arrhythmia Agents / therapeutic use
  • Arrhythmias, Cardiac / epidemiology
  • Automobile Driving* / statistics & numerical data
  • Defibrillators, Implantable
  • Dizziness / epidemiology
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Randomized Controlled Trials as Topic
  • Risk
  • Surveys and Questionnaires
  • Syncope / epidemiology
  • Tachycardia, Ventricular* / drug therapy
  • Tachycardia, Ventricular* / therapy
  • United States

Substances

  • Anti-Arrhythmia Agents