Characterization of multipotent adult progenitor cells, a subpopulation of mesenchymal stem cells

Ann N Y Acad Sci. 2001 Jun:938:231-3; discussion 233-5. doi: 10.1111/j.1749-6632.2001.tb03593.x.

Abstract

Mesenchymal stem cells were isolated and a subpopulation of cells--multipotent adult progenitor cells--were identified that have the potential for multilineage differentiation. Their ability to engraft and differentiate in vivo is under investigation.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Age Factors
  • Animals
  • Becaplermin
  • Bone Marrow Cells / cytology
  • Bone Marrow Transplantation
  • Cell Differentiation
  • Cell Lineage*
  • Cell Separation
  • Cells, Cultured / drug effects
  • Epidermal Growth Factor / pharmacology
  • Humans
  • Mesoderm / cytology*
  • Mice
  • Phenotype
  • Platelet-Derived Growth Factor / pharmacology
  • Proto-Oncogene Proteins c-sis
  • Stem Cell Transplantation
  • Stem Cells / cytology*
  • Stem Cells / drug effects
  • Telomere / ultrastructure

Substances

  • Platelet-Derived Growth Factor
  • Proto-Oncogene Proteins c-sis
  • Becaplermin
  • Epidermal Growth Factor