A new cytotoxic naphthopyrone dimer from Paepalanthus bromelioides

R G Coelho; W Vilegas; K F Devienne; M S Raddi

doi:10.1016/s0367-326x(00)00159-3

A new cytotoxic naphthopyrone dimer from Paepalanthus bromelioides

Fitoterapia. 2000 Sep;71(5):497-500. doi: 10.1016/s0367-326x(00)00159-3.

Authors

R G Coelho¹, W Vilegas, K F Devienne, M S Raddi

Affiliation

¹ Instituto de Química de Araraquara, Departmento de Quimica Organica, CP 355, CEP 14801-970 Araraquara-SP, Brazil.

PMID: 11449496
DOI: 10.1016/s0367-326x(00)00159-3

Abstract

A new naphthopyrone dimer was isolated from the capitula of Paepalanthus bromelioides by chromatographic procedures. It structure was deduced from spectrometric data. On colorimetric assay for cytotoxicity the new dimer showed IC50 of 55.9 microM.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Cells, Cultured / drug effects
Humans
Magnoliopsida*
Naphthalenes / chemistry
Naphthalenes / isolation & purification*
Plant Extracts / chemistry
Plant Extracts / isolation & purification
Plant Extracts / pharmacology
Plants, Medicinal*
Pyrones / chemistry
Pyrones / isolation & purification*

Substances

Naphthalenes
Plant Extracts
Pyrones
naphthopyrone dimer