Catalytic ethenylation reaction of phenol using SnCl4

K Kobayashi; M Yamaguchi

doi:10.1021/ol006888d

Catalytic ethenylation reaction of phenol using SnCl4

Org Lett. 2001 Jan 25;3(2):241-2. doi: 10.1021/ol006888d.

Authors

K Kobayashi¹, M Yamaguchi

Affiliation

¹ Department of Organic Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba, Sendai 980-8578, Japan.

PMID: 11430044
DOI: 10.1021/ol006888d

Abstract

[figure: see text] Ethenylation reaction of phenol with silylethyne at the o-position is catalyzed by the SnCl4-BuLi reagent. While turn over numbers (TONs) in the reactions of m- or p-substituted phenols are 3 to 4, those for o-substituted phenols are 8 to 9.