Do transcriptionally silent BCR-ABL cells persist in CML patients in molecular remission after stem cell transplantation?

Leukemia. 2001 Jun;15(6):997-9. doi: 10.1038/sj.leu.2402136.
No abstract available

Publication types

  • Comparative Study
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Survival
  • Chimera
  • Female
  • Follow-Up Studies
  • Fusion Proteins, bcr-abl / biosynthesis
  • Fusion Proteins, bcr-abl / genetics*
  • Gene Expression Regulation, Leukemic*
  • Hematopoietic Stem Cell Transplantation*
  • Humans
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive / pathology*
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive / therapy
  • Male
  • Minisatellite Repeats
  • Neoplastic Cells, Circulating
  • Neoplastic Stem Cells / pathology*
  • RNA, Messenger / biosynthesis
  • RNA, Neoplasm / biosynthesis
  • Remission Induction
  • Reverse Transcriptase Polymerase Chain Reaction
  • Sensitivity and Specificity
  • Transcription, Genetic*

Substances

  • RNA, Messenger
  • RNA, Neoplasm
  • Fusion Proteins, bcr-abl