A population study in a sample from the Province of Parma was carried out to investigate the polymorphic systems HUMTPOX and HUMCSF1PO. Separation of duplex PCR co-amplified fragments was performed by denaturing PAGE followed by silver staining; seven and six allelic variants respectively were found and frequency distribution was in good agreement with previous studies on Caucasian. The power of Discrimination (PD) was 0.82 and 0.88 respectively and the chance of exclusion (MEC) 0.401 and 0.502; the robustness of the polymorphic systems and informative strength, though not particularly high, suggest the use of these polymorphisms in forensic investigations.