Alcoholic liver disease and apoptosis

Alcohol Clin Exp Res. 2001 May;25(5 Suppl ISBRA):49S-53S. doi: 10.1097/00000374-200105051-00009.

Abstract

This article represents the proceedings of a symposium at the 2000 ISBRA Meeting in Yokohama, Japan. The chairs were Carol A. Casey and Amin Nanji. The presentations were (1) Mechanisms of apoptosis in alcoholic liver disease, by Amin A. Nanji; (2) Impaired receptor-mediated endocytosis: Its role in alcoholic apoptosis, by Carol A. Casey; (3) Toxicity of ethanol in HepG2 cells that express CYP2E1, by Arthur I. Cederbaum; (4) Mitochondrial regulation of ethanol-induced hepatocyte apoptosis, by M. Adachi; and (5) Apoptosis in alcoholic hepatitis, by T. Takahashi.

Publication types

  • Review

MeSH terms

  • Animals
  • Apoptosis / drug effects
  • Apoptosis / physiology*
  • Asialoglycoprotein Receptor
  • Cell Death / drug effects
  • Cell Death / physiology
  • Central Nervous System Depressants / pharmacology
  • Cytochrome P-450 CYP2E1 / drug effects
  • Cytochrome P-450 CYP2E1 / metabolism*
  • Endocytosis / drug effects
  • Endocytosis / physiology*
  • Ethanol / pharmacology
  • Hepatitis, Alcoholic / metabolism
  • Hepatocytes / drug effects
  • Hepatocytes / metabolism
  • Humans
  • Liver Diseases, Alcoholic / metabolism
  • Liver Diseases, Alcoholic / physiopathology*
  • Mitochondria, Liver / drug effects
  • Mitochondria, Liver / metabolism
  • Receptors, Cell Surface / drug effects
  • Receptors, Cell Surface / metabolism

Substances

  • Asialoglycoprotein Receptor
  • Central Nervous System Depressants
  • Receptors, Cell Surface
  • Ethanol
  • Cytochrome P-450 CYP2E1