Experience with the 19-mm Carpentier-Edwards pericardial bioprosthesis in the elderly

Ann Thorac Surg. 2001 May;71(5 Suppl):S249-52. doi: 10.1016/s0003-4975(01)02508-5.

Abstract

Background: Valve replacement in small aortic root remains a surgical challenge. The objective of this study was to compare results of the 19-mm bioprosthesis with those of larger prostheses in the elderly.

Methods: The 443 patients, 70 years of age and older, who underwent aortic valve replacement with Carpentier-Edwards pericardial bioprostheses were reviewed.

Results: There were 93 patients with a mean age of 76+/-4 years with implantation of 19-mm prostheses and 350 patients with a mean age of 75+/-4 years with larger bioprostheses. Associated aortoplasty was performed in 10 patients (11%) with 19-mm bioprostheses and in 8 patients (2%) with larger bioprostheses (p = 0.001). There were 11 deaths (12%) within 30 days of surgery in patients with 19-mm prostheses and 22 deaths (6%) among those with larger prostheses (p = 0.1). The 7-year survival rate averaged 61%+/-7% in patients with 19-mm prostheses and 67%+/-4% in those with larger prostheses (p = 0.8). The 7-year freedom rates from all valve-related events averaged 96%+/-2% and 93%+/-2%, respectively (p = 0.6).

Conclusions: Aortic valve replacement with the 19-mm Carpentier-Edwards pericardial bioprosthesis offers excellent midterm results in the elderly.

Publication types

  • Comparative Study

MeSH terms

  • Actuarial Analysis
  • Aged
  • Aged, 80 and over
  • Aortic Valve / surgery*
  • Bioprosthesis*
  • Female
  • Follow-Up Studies
  • Heart Valve Prosthesis*
  • Humans
  • Male
  • Postoperative Complications / mortality
  • Prosthesis Design
  • Prosthesis Failure
  • Prosthesis Fitting*
  • Survival Rate