In utero intervention in a patient with prune-belly syndrome and severe urethral hypoplasia

Urology. 2001 Jun;57(6):1178. doi: 10.1016/s0090-4295(01)00951-7.

Abstract

Prenatal ultrasound scanning of a 20-year-old woman at 17 weeks of gestation revealed findings suggestive of bladder outlet obstruction, including bladder distension, dilated bilateral ureters, urinary ascites, and oligohydramnios. Vesicoamniotic shunts were placed with decompression of the bladder and correction of the amniotic fluid levels. Labor was induced at 36 weeks' gestation. At birth, the infant was noted to have prune-belly syndrome with severe urethral hypoplasia, a variant usually associated with a poor prognosis, necessitating vesicostomy for bladder drainage. We present a case of a patient with prune-belly syndrome and bladder outlet obstruction in whom early intervention resulted in an excellent outcome with preservation of renal and pulmonary function.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Ascites / congenital
  • Ascites / diagnostic imaging
  • Ascites / therapy
  • Catheterization / methods*
  • Female
  • Fetal Diseases / diagnostic imaging
  • Fetal Diseases / therapy*
  • Humans
  • Male
  • Oligohydramnios / diagnostic imaging
  • Oligohydramnios / therapy
  • Pregnancy
  • Prune Belly Syndrome / diagnostic imaging
  • Prune Belly Syndrome / therapy*
  • Ultrasonography, Prenatal
  • Urinary Bladder Neck Obstruction / congenital
  • Urinary Bladder Neck Obstruction / diagnostic imaging
  • Urinary Bladder Neck Obstruction / therapy*
  • Urine