Secondary chronic myelogenous leukemia after autologous peripheral blood stem cell transplantation for lymphoma

Int J Hematol. 2001 Jan;73(1):126-8. doi: 10.1007/BF02981915.

Abstract

A 31-year-old woman was diagnosed with intestinal lymphoma (high-grade mucosa-associated lymphoid tissue lymphoma, stage IIE) in September 1996. Eleven courses of chemotherapy were administered, but the results were poor. She received autologous peripheral blood stem cell transplantation (PBSCT) in September 1997. Leukocytosis was noted, and chronic myelogenous leukemia was diagnosed 8 months after the PBSCT, progressing to blast phase 10 months later. We report this case because secondary chronic myelogenous leukemia after stem cell transplantation is rare.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antineoplastic Agents / administration & dosage
  • Female
  • Hematopoietic Stem Cell Transplantation / adverse effects*
  • Humans
  • Intestinal Neoplasms / pathology
  • Intestinal Neoplasms / therapy
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive / diagnosis
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive / etiology*
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive / pathology
  • Lymphoma, B-Cell, Marginal Zone / pathology
  • Lymphoma, B-Cell, Marginal Zone / therapy*
  • Neoplasms, Second Primary / etiology*
  • Neoplasms, Second Primary / pathology
  • Transplantation, Autologous / adverse effects

Substances

  • Antineoplastic Agents