[Adhesion of erythrocytes of patients with transient ischemic attack to injured endothelial cells]

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 1997 Dec;14(4):349-52, 358.
[Article in Chinese]

Abstract

Adherence of erythrocytes of patients with transient ischemic attack(TIA) to human umbilical vein endothelial cells(HUVEC) treated with H2O2 were quantitatively studied in the flow chamber system. The results showed that injured HUVECs enhanced the adherence of erythrocytes to endothelial cells in patients with TIA. The increased adhesion of erythrocytes to endothelial cells might promote the vascular damage. Consequently endothelium might play an important role in the increased adhesiveness of TIA RBC to endothelial cells.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Cell Adhesion
  • Cells, Cultured
  • Endothelium, Vascular / drug effects
  • Endothelium, Vascular / pathology*
  • Endothelium, Vascular / physiopathology
  • Erythrocytes / physiology*
  • Female
  • Fetus
  • Humans
  • Hydrogen Peroxide / pharmacology
  • Ischemic Attack, Transient / blood*
  • Ischemic Attack, Transient / physiopathology
  • Male
  • Middle Aged
  • Umbilical Veins / cytology

Substances

  • Hydrogen Peroxide