Targeted inactivation of the sodium-calcium exchanger (Ncx1) results in the lack of a heartbeat and abnormal myofibrillar organization

FASEB J. 2001 May;15(7):1209-11. doi: 10.1096/fj.00-0696fje.
No abstract available

MeSH terms

  • Animals
  • Calcium / metabolism
  • Embryonic and Fetal Development
  • Gene Targeting
  • Genes, Reporter
  • Heart / anatomy & histology
  • Heart / embryology*
  • Heart / physiology*
  • Immunohistochemistry
  • Mice
  • Mice, Transgenic
  • Morphogenesis
  • Myocardial Contraction / physiology*
  • Myocardium / metabolism
  • Myocardium / ultrastructure
  • Sodium-Calcium Exchanger / genetics
  • Sodium-Calcium Exchanger / metabolism*

Substances

  • Sodium-Calcium Exchanger
  • sodium-calcium exchanger 1
  • Calcium