Fetal splenic rupture following transfusion

Obstet Gynecol. 2001 May;97(5 Pt 2):824-5. doi: 10.1016/s0029-7844(00)01218-7.

Abstract

Background: Splenic rupture in the newborn is a rare complication in erythroblastosis fetalis. There are no reports of splenic rupture in the fetus affected by hemolytic disease of the newborn.

Case: A 41-year-old gravida 3, para 2-0-0-2 with severe rhesus alloimmunization was managed with serial intrauterine transfusions resulting in fetal death after the fourth procedure. Autopsy findings revealed intra-abdominal clotted blood and splenic capsular defects consistent with splenic rupture.

Conclusion: Fetal splenic rupture might occur in hemolytic disease of the newborn associated with splenomegaly. Acute hemodynamic changes with increased intra-abdominal pressure from intrauterine transfusion might precipitate splenic rupture. (Obstet Gynecol 2001;97:824-5.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Blood Transfusion, Intrauterine / adverse effects*
  • Erythroblastosis, Fetal / therapy*
  • Female
  • Fetal Death
  • Humans
  • Pregnancy
  • Pregnancy Complications, Hematologic / therapy*
  • Prenatal Care
  • Rh Isoimmunization / therapy*
  • Rupture, Spontaneous
  • Splenomegaly / etiology*