[Reduction of hematogenous infection in HIV positive patients following highly active antiretroviral therapy]

Med Clin (Barc). 2001 Feb 24;116(7):256-8. doi: 10.1016/s0025-7753(01)71788-5.
[Article in Spanish]

Abstract

Background: Bloodstream infections have probably decreased in HIV patients since highly active antiretroviral therapy (HAART) usage.

Patients and method: Hematogenous infections, including mycobacteria and fungi in HIV patients, stratified into two periods (I: 1995-1996 and II: 1997-1998) were included to evaluate changes attributable to HAART.

Results: 226 episodes were attended (incidence: 38.8 in period I and 15.3 in period II; p < 0.01). A significant decrease was observed in immunosuppression related microorganisms. HAART usage increased from 6.4% in period I to 31.2% in period II. Immunological parameters of HIV patients significantly improved in period II.

Conclusions: Hematogenous infections have significantly decreased in HIV patients since the use of HAART.

Publication types

  • English Abstract

MeSH terms

  • AIDS-Related Opportunistic Infections / epidemiology*
  • Adult
  • Anti-HIV Agents / therapeutic use
  • Antiretroviral Therapy, Highly Active*
  • CD4 Lymphocyte Count
  • Female
  • HIV Infections / drug therapy*
  • HIV Infections / immunology
  • Humans
  • Male
  • Sepsis / epidemiology*

Substances

  • Anti-HIV Agents