Radiation therapy of brain tumors in children

Radiology. 1975 Jun;115(3):687-93. doi: 10.1148/15.3.687.

Abstract

The case histories of 124 children irradiated for brain tumors were reviewed to determine survival rate and functional prognosis, with special reference to somatic growth. Five-year survival rates (29% of 97 patients with gliomas and 70% of 27 patients with non-gliomatous tumors) were approximately the same as in our adult series, despite the differences in histology and predilection. Although 70% of 42 long-term survivors had active, useful lives, stunted growth was observed in 15 of them. More attention should be directed to the growth of children irradiated for brain tumors.

MeSH terms

  • Adolescent
  • Astrocytoma / radiotherapy
  • Brain Neoplasms / radiotherapy*
  • Brain Stem
  • Cerebellar Neoplasms / radiotherapy
  • Cerebral Ventricle Neoplasms / radiotherapy
  • Child
  • Child, Preschool
  • Cobalt Radioisotopes / therapeutic use
  • Craniopharyngioma / radiotherapy*
  • Ependymoma / radiotherapy*
  • Female
  • Gamma Rays
  • Glioma / radiotherapy*
  • Growth Disorders / etiology
  • Humans
  • Infant
  • Male
  • Medulloblastoma / radiotherapy*
  • Meningioma / radiotherapy*
  • Mesencephalon
  • Oligodendroglioma / radiotherapy
  • Pinealoma / radiotherapy
  • Pituitary Neoplasms / radiotherapy
  • Prognosis
  • Radiotherapy / adverse effects
  • X-Rays

Substances

  • Cobalt Radioisotopes