Abstract
The case histories of 124 children irradiated for brain tumors were reviewed to determine survival rate and functional prognosis, with special reference to somatic growth. Five-year survival rates (29% of 97 patients with gliomas and 70% of 27 patients with non-gliomatous tumors) were approximately the same as in our adult series, despite the differences in histology and predilection. Although 70% of 42 long-term survivors had active, useful lives, stunted growth was observed in 15 of them. More attention should be directed to the growth of children irradiated for brain tumors.
MeSH terms
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Adolescent
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Astrocytoma / radiotherapy
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Brain Neoplasms / radiotherapy*
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Brain Stem
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Cerebellar Neoplasms / radiotherapy
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Cerebral Ventricle Neoplasms / radiotherapy
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Child
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Child, Preschool
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Cobalt Radioisotopes / therapeutic use
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Craniopharyngioma / radiotherapy*
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Ependymoma / radiotherapy*
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Female
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Gamma Rays
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Glioma / radiotherapy*
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Growth Disorders / etiology
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Humans
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Infant
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Male
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Medulloblastoma / radiotherapy*
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Meningioma / radiotherapy*
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Mesencephalon
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Oligodendroglioma / radiotherapy
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Pinealoma / radiotherapy
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Pituitary Neoplasms / radiotherapy
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Prognosis
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Radiotherapy / adverse effects
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X-Rays