Dynamic arc radiosurgery and radiotherapy: commissioning and verification of dose distributions

Int J Radiat Oncol Biol Phys. 2001 Apr 1;49(5):1451-60. doi: 10.1016/s0360-3016(01)01436-5.

Abstract

Purpose: Conformal stereotactic radiosurgery and radiotherapy using a linear accelerator and a micromultileaf collimator (mMLC) offer the possibility of irradiating irregularly shaped target volumes. Dynamic arc radiosurgery and radiotherapy, i.e., stereotactic radiation therapy combining a moving gantry with a dynamic mMLC, enable the radiation even of lesions with concave structures.

Methods and materials: The dynamic arc method requires additional tools for quality assurance (QA) and three-dimensional verification at a high spatial resolution. A QA program was developed. Dose distributions of planning target volumes with concavities were investigated in polymer gel phantoms. The radiation-induced change of the relaxation rate R(2) was measured by magnetic resonance imaging. The distributions were compared with image processing tools.

Results: Using the therapy-planning software BrainSCAN 4.0 (and 4.1 beta) in combination with the mMLC m3, deviations between the planned and measured 90% isodoses of about 2 mm were registered in the isocenter plane. Three-dimensional verification was feasible in the range of accuracy achieved in planning and dose measurement.

Conclusions: Dynamic arc radiosurgery and radiotherapy offer excellent conformation even for complicated planning target volumes with concavities. The dose distribution calculated with the treatment-planning software used can be accomplished with the available equipment. Patients can be treated by dynamic arc radiosurgery and radiotherapy.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Calibration
  • Combined Modality Therapy
  • Humans
  • Magnetic Resonance Imaging
  • Particle Accelerators
  • Phantoms, Imaging*
  • Physical Phenomena
  • Physics
  • Quality Control
  • Radiosurgery / instrumentation
  • Radiosurgery / methods*
  • Radiosurgery / standards
  • Radiotherapy Dosage
  • Radiotherapy Planning, Computer-Assisted / instrumentation
  • Radiotherapy Planning, Computer-Assisted / methods*
  • Radiotherapy Planning, Computer-Assisted / standards
  • Radiotherapy, Conformal / instrumentation
  • Radiotherapy, Conformal / methods*
  • Radiotherapy, Conformal / standards