Unsuspected recurrent pituitary adenoma presenting as an orbital mass

Ophthalmic Plast Reconstr Surg. 2001 Mar;17(2):140-3. doi: 10.1097/00002341-200103000-00014.

Abstract

Purpose: Orbital invasion of pituitary tumors is rare and usually accompanied by optic nerve head pallor and visual loss. We describe a case of unilateral massive orbital invasion by a recurrent pituitary tumor with preserved visual acuity and normal optic nerve appearance.

Methods: Case report.

Results: Progressive proptosis developed 15 years after transphenoidal removal of a pituitary tumor. Based on the radiological appearance and the clinical history, the patient was suspected to have a sphenoid wing meningioma secondary to previous radiation treatment. A combined neurosurgical and orbital approach was used to remove the intraorbital mass, which extended from the cranial cavity through the superior orbital fissure and the optic canal. Histopathologic examination demonstrated a recurrent nonsecreting pituitary adenoma.

Conclusions: Orbital extension of a recurrent pituitary adenoma should be considered in the differential diagnosis of progressive proptosis even in the absence of significant optic neuropathy.

Publication types

  • Case Reports

MeSH terms

  • Adenoma / pathology*
  • Adenoma / surgery
  • Diagnosis, Differential
  • Exophthalmos / diagnosis
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Middle Aged
  • Neoplasm Invasiveness
  • Neoplasm Recurrence, Local
  • Orbital Neoplasms / diagnosis*
  • Orbital Neoplasms / surgery
  • Pituitary Neoplasms / pathology*
  • Pituitary Neoplasms / surgery