Epoxides and aziridines from diazoacetates via ylide intermediates

Org Lett. 2001 Mar 22;3(6):933-5. doi: 10.1021/ol015600x.

Abstract

An effective methodology is reported for stereospecific epoxidation and aziridination via carbonyl ylide intermediates using rhodium(II) acetate catalyzed reactions of phenyl- and styryldiazoacetates with aldehydes, ketones, or imines.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Acetates / chemistry*
  • Aziridines / chemical synthesis*
  • Aziridines / chemistry
  • Azo Compounds / chemistry*
  • Epoxy Compounds / chemical synthesis*
  • Epoxy Compounds / chemistry
  • Indicators and Reagents
  • Models, Molecular
  • Molecular Conformation
  • Molecular Structure
  • Stereoisomerism

Substances

  • Acetates
  • Aziridines
  • Azo Compounds
  • Epoxy Compounds
  • Indicators and Reagents