Association of white blood cell count with increased mortality in acute myocardial infarction and unstable angina pectoris. OPUS-TIMI 16 Investigators

Am J Cardiol. 2001 Mar 1;87(5):636-9, A10. doi: 10.1016/s0002-9149(00)01444-2.

Abstract

We observed in a study of 7,651 patients with acute coronary syndromes that a white blood cell (WBC) count of > 10,000 was associated with increased 30-day and 10-month mortality (6.2% vs 3.2% to 3.6% for WBC count < 10,000; p < 0.000). With its simplicity and widespread availability, WBC count could serve as a simple, inexpensive, new tool for risk stratification in acute coronary syndromes.

Publication types

  • Clinical Trial
  • Comparative Study
  • Multicenter Study
  • Randomized Controlled Trial

MeSH terms

  • Aged
  • Alanine / administration & dosage
  • Angina, Unstable / drug therapy
  • Angina, Unstable / immunology
  • Angina, Unstable / mortality*
  • Female
  • Follow-Up Studies
  • Humans
  • Leukocyte Count*
  • Male
  • Middle Aged
  • Myocardial Infarction / drug therapy
  • Myocardial Infarction / immunology
  • Myocardial Infarction / mortality*
  • Platelet Aggregation Inhibitors / administration & dosage
  • Pyrrolidines / administration & dosage
  • Risk Factors
  • Survival Rate

Substances

  • Platelet Aggregation Inhibitors
  • Pyrrolidines
  • orbofiban
  • Alanine