Amelanotic corneal melanoma after a blast injury

Am J Ophthalmol. 2001 Feb;131(2):259-60. doi: 10.1016/s0002-9394(00)00780-7.

Abstract

Purpose: To report a case of a corneal melanoma after trauma.

Methods: Case report.

Results: A 68-year-old man sustained an ocular injury from a blast furnace explosion in 1958. In 1998, he underwent a penetrating keratoplasty for a corneal scar. Histologic examination and cell markers of the host button revealed intrastromal and subepithelial melanoma. No clinical or microscopic evidence of adjacent conjunctival or uveal melanoma was found.

Conclusion: Melanoma of the cornea can present as a stromal opacity after trauma.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Biomarkers, Tumor / analysis
  • Blast Injuries / complications*
  • Corneal Diseases / etiology*
  • Corneal Diseases / pathology
  • Corneal Diseases / surgery
  • Corneal Injuries*
  • Eye Injuries / complications*
  • Eye Neoplasms / etiology*
  • Eye Neoplasms / pathology
  • Eye Neoplasms / surgery
  • Humans
  • Keratoplasty, Penetrating
  • Male
  • Melanoma, Amelanotic / etiology*
  • Melanoma, Amelanotic / pathology
  • Melanoma, Amelanotic / surgery

Substances

  • Biomarkers, Tumor