[Some prognostic factors in the combined therapy of locally advanced breast cancer]

E K Voznyĭ; V P Kharchenko; S N Gurov; N Iu Dobrovol'skaia; S A Bol'shakova

[Some prognostic factors in the combined therapy of locally advanced breast cancer]

Vopr Onkol. 2000;46(6):732-6.

[Article in Russian]

Authors

E K Voznyĭ¹, V P Kharchenko, S N Gurov, N Iu Dobrovol'skaia, S A Bol'shakova

Affiliation

¹ Russian Center for Roentgenology Research, Ministry of Health of the RF, Moscow.

PMID: 11219949

Abstract

A relationship between the dynamics of growth and pathological response of tumor cells and the number of neoadjuvant chemotherapy courses was established. As a result, there was no correlation between increase in overall and disease-free survival, on the one hand, and stage, on the other. An interval between neoadjuvant chemotherapy and surgery longer than 4 weeks had a negative effect on overall tumor response and duration of disease-free period.

Publication types

English Abstract

MeSH terms

Adult
Aged
Antineoplastic Combined Chemotherapy Protocols / administration & dosage*
Breast Neoplasms / drug therapy
Breast Neoplasms / mortality
Breast Neoplasms / pathology*
Breast Neoplasms / surgery
Breast Neoplasms / therapy*
Chemotherapy, Adjuvant
Combined Modality Therapy
Disease-Free Survival
Female
Humans
Middle Aged
Neoadjuvant Therapy
Neoplasm Staging
Predictive Value of Tests
Prognosis
Risk Factors
Survival Analysis
Time Factors
Treatment Outcome