Probing the interface between membrane proteins and membrane lipids by X-ray crystallography

Trends Biochem Sci. 2001 Feb;26(2):106-12. doi: 10.1016/s0968-0004(00)01746-1.

Abstract

Biological membranes are composed of a complex mixture of lipids and proteins, and the membrane lipids support several key biophysical functions, in addition to their obvious structural role. Recent results from X-ray crystallography are shedding new light on the precise molecular details of the protein-lipid interface.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Bacteriorhodopsins / chemistry
  • Cardiolipins / chemistry
  • Cell Membrane / chemistry*
  • Cell Membrane / metabolism
  • Crystallography, X-Ray / methods*
  • Electron Transport Complex IV / chemistry
  • Lipid Metabolism
  • Lipids / chemistry*
  • Models, Molecular
  • Photosynthetic Reaction Center Complex Proteins / chemistry

Substances

  • Cardiolipins
  • Lipids
  • Photosynthetic Reaction Center Complex Proteins
  • Bacteriorhodopsins
  • Electron Transport Complex IV