Gamma knife radiosurgery using 90 Gy for trigeminal neuralgia

J Neurosurg. 2000 Dec:93 Suppl 3:152-4. doi: 10.3171/jns.2000.93.supplement.

Abstract

Object: The purpose of this paper was to assess the treatment of trigeminal neuralgia (TN) with the higher than normal dose of 90 Gy.

Methods: Forty-two patients with typical TN were treated over a 3-year period with gamma knife radiosurgery. Every patient received a maximum dose of 90 Gy in a single 4-mm isocenter targeted to the root entry zone of the trigeminal nerve. Thirty of 42 patients had undergone no prior treatments. The median follow-up period was 14 months (range 2-30 months). Thirty-one patients (73.8%) achieved complete relief of pain. Nine patients (21.4%) obtained good pain control. Complications were limited to increased facial paresthesia in seven patients (16.7%) and dysgeusia in four patients (9.5%).

Conclusions: The authors conclude that the use of 90 Gy is a safe and effective dose for the treatment of TN.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Radiosurgery*
  • Reoperation
  • Spinal Nerve Roots / surgery
  • Treatment Outcome
  • Trigeminal Neuralgia / diagnosis
  • Trigeminal Neuralgia / etiology
  • Trigeminal Neuralgia / surgery*