Premorbid performance IQ deficit in schizophrenia

Acta Psychiatr Scand. 2000 Dec;102(6):414-22. doi: 10.1034/j.1600-0447.2000.102006414.x.

Abstract

Objective: Performance IQ (PIQ) is often lower than verbal IQ (VIQ) in schizophrenic patients. Whether PIQ < VIQ precedes psychotic symptoms in schizophrenia remains uncertain.

Method: We investigated premorbid IQ scores in 63 subjects assessed at a child and adolescent psychiatric unit (mean age 13.1 years, SD 3.2), who at follow-up in adulthood (mean age 30.9 years, SD 3.9) received a lifetime RDC diagnosis of schizophrenia-related psychosis, affective disorder, or no psychiatric disorder.

Results: Premorbid PIQ < VIQ significantly differentiated the groups with schizophrenia-related psychosis and no psychiatric disorder. Subjects with schizophrenia-related psychosis had a significantly lower mean value for premorbid PIQ, but not VIQ, compared to subjects who developed affective disorder or subjects without psychiatric disorder.

Conclusion: Our results emphasize premorbid intellectual deficits in schizophrenia. Those deficits might largely be in consequence of an impairment on the PIQ scale.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Child
  • Cognition Disorders / psychology*
  • Female
  • Follow-Up Studies
  • Humans
  • Intelligence*
  • Male
  • Predictive Value of Tests
  • Prognosis
  • Schizophrenic Psychology*
  • Verbal Behavior